Азев Вячеслав Николаевич

Преподаваемая дисциплина:
Основы современного пептидного синтеза

Основные публикации за последние 5 лет:

• Grishin SY, Deryusheva EI, Machulin AV, Selivanova OM, Glyakina AV, Gorbunova EY, Mustaeva LG, Azev VN, Rekstina VV, Kalebina TS, Surin AK, Galzitskaya OV (2020). Amyloidogenic propensities of ribosomal s1 proteins: Bioinformatics screening and experimental checking. Int J Mol Sci 21 (15), 1–19
• Zolotarev YA, Dadayan AK, Kozik VS, Shram SI, Azev VN, Bogachouk AP, Lipkin VM, Myasoedov NF (2019). Pharmacokinetics of HLDF-6-AA Peptide in the Organism of Experimental Animals. J. Bioorganic Chem. 45 (6), 514–521
• Zolotarev YuA, Dadayan AK, Kozik VS, Shram SI, Nagaev IYu, Azev VN, Bogachouk AP, Lipkin VM, Myasoedov NF (2019). Proteolytic Hydrolysis of the Antitumor Peptide HLDF-6-AA in Blood Plasma. J. Bioorganic Chem. 45 (5), 347–352
• (патент) ДанилковичАВ, Туробов ВИ, Мустаева ЛГ, Горбунова ЕЮ, Полякова АИ, Удовиченко ИП, Азев ВН, Мурашев АН, Липкин ВМ (2019). Актг-подобный пептид с иммуносупрессорной функцией. RU2681317C1 Россия №RU2017140866A (изобретение)
• (патент) АзевВН, Туробов ВИ, Данилкович АВ, Шевелёв АБ, Позднякова НВ, Чулин АН, Мустаева ЛГ, Горбунова ЕЮ, Мурашев АН, Липкин ВМ, Удовиченко ИП (2019). Способ получения иммуносупрессорного пептида Abu-TGIRIS-Abu, меченного ионом Gd3+. RU2681318C1 Россия №RU2017140995A (изобретение)
• (патент) Туробов ВИ, Данилкович АВ, Шевелёв АБ, Бирюкова ЮК, Азев ВН, Мурашев АН, Липкин ВМ, Удовиченко ИП (2018). Пептид из состава тяжелой цепи иммуноглобулина человека, пригодный для лечения рассеянного склероза. RU2646817 Россия №2016151603 (изобретение)
• Turobov VI, Azev VN, Shevelev AB, Pozdniakova NV, Biryukova YK, Murashev AN, Lipkin VM, Udovichenko IP (2018). Immunosuppressant Peptide Abu-TGIRIS-Abu-NH2and its Application for Treatment of Multiple Sclerosis. Bionanoscience 8 (1), 484–489
• Turobov VI, Danilkovich AV, Shevelev AB, Biryukova YK, Pozdniakova NV, Azev VN, Murashev AN, Lipkin VM, Udovichenko IP (2018). Efficacy of synthetic peptide corresponding to the ACTH-like sequence of human immunoglobulin G1 in experimental autoimmune encephalomyelitis. Front Pharmacol 9 (FEB), 113
• Zolotarev YA, Kovalev GI, Kost NV, Voevodina ME, Sokolov OY, Dadayan AK, Kondrakhin EA, Vasileva EV, Bogachuk AP, Azev VN, Lipkin VM, Myasoedov NF (2017). Anxiolytic activity of the neuroprotective peptide HLDF-6 and its effects on brain neurotransmitter systems in BALB/c and C57BL/6 mice. J Psychopharmacol 30 (9), 922–935
• Rzhevskiy DI, Kravchenko IN, Sadovnikova ES, Rasskazova EA, Novikova NN, Ponomareva TI, Bondarenko DA, Semushina SG, Dyachenko IA, Shayhutdinova ER, Pakhomova IA, Kalabina EA, Zinchenko DV, Bogachuk AP, Azev VN, Lipkin VM, Murashev AN (2017). Preclinical safety studies of the drug with nootropic activity, based on the amide form of the leukocytes differentiation factor fragment. Russian Journal of Biopharmaceuticals 9 (4), 50–56
• Selivanova OM, Glyakina AV, Gorbunova EY, Mustaeva LG, Suvorina MY, Grigorashvili EI, Nikulin AD, Dovidchenko NV, Rekstina VV, Kalebina TS, Surin AK, Galzitskaya OV (2016). Structural model of amyloid fibrils for amyloidogenic peptide from Bgl2p–glucantransferase of S. cerevisiae cell wall and its modifying analog. New morphology of amyloid fibrils. BIOCHIM BIOPHYS ACTA 1864 (11), 1489–1499
• Zakharchenko NS, Rukavtsova EB, Shevchuk TV, Furs OV, Pigoleva SV, Lebedeva AA, Chulina IA, Baidakova LK, Buryanov YI (2016). The obtainment and characteristics of Kalanchoe pinnata L. plants expressing the artificial gene of the cecropin P1 antimicrobial peptide. APPL BIOCHEM MICRO+ 52 (4), 421–428
• Selivanova OM, Gorbunova EY, Mustaeva LG, Grigorashvili EI, Suvorina MY, Surin AK, Galzitskaya OV (2016). Peptide Aβ(16-25) forms nanofilms in the process of its aggregation. Biochemistry (Mosc) 81 (7), 755–761
• Khrenova MG, Solovyev ID, Azev VN, Lapshin GD, Savitsky AP (2016). Oxoethylene derivative of the natural substrate as an inhibitor of matrix metalloproteinase MMP-2. MENDELEEV COMMUN 26 (3), 207–208
• Bogachouk AP, Storozheva ZI, Solovjeva OA, Sherstnev VV, Zolotarev YA, Azev VN, Rodionov IL, Surina EA, Lipkin VM (2016). Comparative study of the neuroprotective and nootropic activities of the carboxylate and amide forms of the HLDF-6 peptide in animal models of Alzheimer’s disease. J Psychopharmacol 30 (1), 78–92
• Zolotarev A, Dadayan AK, Kost NV, Voevodina ME, Sokolov OY, Kozik VS, Shram SI, Azev VN, Bocharov EV, Bogachouk AP, Lipkin VM, Myasoedov NF (2015). The Qualitative Analysis of the Amide Derivative of HLDF-6 Peptide and Its Metabolites with the Use of Tritium- and Deuterium-Labeled Derivatives. Bioorg Khim 41 (6), 644–656
• Zolotarev YA, Dadayan AK, Kost NV, Voevodina ME, Sokolov OY, Kozik VS, Shram SI, Azev VN, Bocharov EV, Bogachouk AP, Lipkin VM, Myasoedov NF (2015). The qualitative analysis of the amide of the HLDF-6 peptide and its metabolites in tissues of laboratory animals with the use of tritium-labeled and deuterium-labeled derivatives. J. Bioorganic Chem. 41 (6), 578–589
• Laman AG, Lathe R, Savinov GV, Shepelyakovskaya AO, Boziev KM, Baidakova LK, Chulin AN, Brovko FA, Svirshchevskaya EV, Kotelevtsev Y, Eliseeva IA, Guryanov SG, Lyabin DN, Ovchinnikov LP, Ivanov VT (2015). Innate immunity: Bacterial cell-wall muramyl peptide targets the conserved transcription factor YB-1. FEBS Lett 589 (15), 1819–1824.